導(dǎo)師簡介

姓名：郎小娥 性別：女政治面貌：民革黨員學(xué)歷：博士研究生畢業(yè)學(xué)位：醫(yī)學(xué)博士職稱：主任醫(yī)師博、碩導(dǎo)師：博導(dǎo)和碩導(dǎo)本崗位工作年數(shù)：40.5年

研究方向：

精神分裂癥與抑郁癥的基礎(chǔ)與臨床研究

榮譽稱號：

（1）山西省“三晉英才-拔尖骨干人才”

（2）獲2023年度山西省科技進(jìn)步二等獎

（3）獲2019年度山西省科技進(jìn)步二等獎

（4）2022年度郎小娥以第一發(fā)明人授權(quán)國際發(fā)明專利1項

學(xué)術(shù)任職：

中華醫(yī)學(xué)會精神病學(xué)分會網(wǎng)絡(luò)精神病學(xué)組委員

中國醫(yī)師協(xié)會醫(yī)學(xué)科普分會精神心理專委會委員

中國民族衛(wèi)生協(xié)會心理健康分會常務(wù)理事

中國藥物濫用防治協(xié)會理事

山西省老年醫(yī)學(xué)學(xué)會精神醫(yī)學(xué)分會主任委員

山西省精神科?？坡?lián)盟醫(yī)療質(zhì)控中心主任

近五年承擔(dān)科研課題情況：

(1)中央引導(dǎo)地方科技發(fā)展資金項目（自由探索類基礎(chǔ)研究）,項目名稱：首發(fā)分裂癥糖代謝紊亂介導(dǎo)“腦SC-FC耦合”異常的機制研究,項目編號：YDZJSX2022A064,主持

(2)山西省“136興醫(yī)工程”領(lǐng)軍臨床專科專項（136專項）,項目名稱：首發(fā)精神分裂癥海馬體積、血漿蛋白質(zhì)組分與P50改變之間交互作用的機制研究,項目編號：Y2022136006，主持

代表性論著及近五年的代表性論文（限10項以內(nèi)）：

近五年郎小娥以第一作者和/或通訊作者發(fā)表的10篇SCI代表性論文

[1]Xiaoe Lang,Mei Xue,Xiaocui Zang,Fengchun Wu*,Meihong Xiu*,Xiangyang Zhang*. Efficacy of low-dose risperidone in combination with sertraline in first-episode drug-na?ve patients with schizophrenia: a randomized controlled open-label study [J]. J Transl Med, 2023, 21(1): 432.（唯一第一作者中科院2區(qū)IF：6.1）

[2]Meihong Xiu, Lei Zhao, Qianqian Sun,Xiaoe Lang*. Efficacy of Low-dose Olanzapine in Combination with Sertraline on Negative Symptoms and Psychosocial Functioning in Schizophrenia: A Randomized Controlled Trial [J]. Curr Neuropharmacol, 2024，22（8）：1406-1413.（唯一通訊作者中科院2區(qū)IF：4.8）

[3]Xiaoe Lang*, Dongmei Wang, Dachun Chen, Meihong Xiu, Huixia Zhou, Li Wang, Bo Cao*, Xiangyang Zhang*. Association Between Hippocampal Subfields and Clinical Symptoms of First-Episode and Drug Naive Schizophrenia Patients During 12 Weeks of Risperidone Treatment [J]. Neurotherapeutics, 2022, 19(1): 399-407.（唯一第一作者/共同通訊作者中科院2區(qū)IF:5.7）

[4] Meihong Xiu, Meng Hao, Cai Liu, Maodi Sun,Xiaoe Lang*.Glucose Metabolism and Sex Hormones in Male Patients with Medication-na?ve First-episode Schizophrenia: A Large-scale Cross-sectional Study[J].Curr Neuropharmacol, 2024;22(13):2263-2270.（唯一通訊作者中科院2區(qū)IF:4.8）

[5] Meihong Xiu, Wenxin Li, Yu Lan, Kaiwen Li,Xiaoe Lang*. Differentiation Across Bipolar Disorder and Major Depressive Disorder by Whole-Night Polysomnographic Findings. J Clin Psychiatry, 2024 ,14;85(3):23m15210.（唯一通訊作者中科院2區(qū)IF:4.5）

[6]Xiaoe Lang,Xiaocui Zang, Feng Yu, Meihong Xiu*. Effects of low-dose combined olanzapine and sertraline on negative and depressive symptoms in treatment-resistant outpatients with acute exacerbated schizophrenia [J]. Front Pharmacol, 2023, 14(1166507.（唯一第一作者中科院2區(qū)IF：4.4）

[7]Mei Hong Xiu,XiaoE Lang*, Da Chun Chen, Bo Cao, Thomas R. Kosten,Raymond Y. Cho, Hui Shi, Chang Wei Wei, An Shi Wu, Xiang Yang Zhang*.Cognitive Deficits and Clinical Symptoms with Hippocampal Subfields in First-Episode and Never-Treated Patients with Schizophrenia [J]. Cereb Cortex, 2021, 31(1): 89-96.（共同通訊作者中科院2區(qū)IF：4.861）

[8]Xiaoe Lang, Yang Zhou, Lei Zhao, Yinjun Gu, Xi Wu, Yuefeng Zhao, Zezhi Li*, Xiangyang Zhang*.Differences in patterns of metabolic abnormality and metabolic syndrome between early-onset and adult-onset first-episode drug-naive schizophrenia patients [J]. Psychoneuroendocrinology, 2021, 132(105344.（唯一第一作者中科院2區(qū)IF：4.693）

[9]Xiaoe Lang*, Dongmei Wang, Huixia Zhou, Li Wang, Thomas R. Kosten, Xiang-Yang Zhang*.P50 inhibition defects, psychopathology and gray matter volume in patients with first-episode drug-naive schizophrenia [J]. Asian J Psychiatr, 2023, 80(103421.（唯一第一作者/共同通訊作者中科院4區(qū)IF:9.5）

[10]Xiaoe Lang, Qinqin Liu, Hanliu Fang, Yongjie Zhou, Mattew T. Forster, Zezhi Li*, Xiangyang Zhang*.The prevalence and clinical correlates of metabolic syndrome and cardiometabolic alterations in 430 drug-naive patients in their first episode of schizophrenia [J]. Psychopharmacology, 2021, 238(12): 3643-52.（唯一第一作者中科院3區(qū)IF：4.415）