導(dǎo)師簡(jiǎn)介

姓名：李艷麗性別：女政治面貌：中共黨員學(xué)歷：研究生 學(xué)位：博士職稱：副教授

博、碩導(dǎo)師：碩導(dǎo)本崗位工作年數(shù)：5

研究方向：衰老及認(rèn)知障礙的機(jī)制研究

榮譽(yù)稱號(hào)：無(wú)

學(xué)術(shù)任職：無(wú)

近五年承擔(dān)科研課題情況：

國(guó)家自然科學(xué)基金青年項(xiàng)目 項(xiàng)目名稱：腸道菌群調(diào)控Treg細(xì)胞參與衰老相關(guān)認(rèn)知下降的作用和機(jī)制研究，項(xiàng)目編號(hào): 82101641

山西省基礎(chǔ)研究計(jì)劃青年項(xiàng)目 項(xiàng)目名稱：腸道菌群通過(guò)抑制炎癥促進(jìn)健康老齡化，項(xiàng)目編號(hào): 20210302124173

代表性論著及近五年的代表性論文（限10項(xiàng)以內(nèi)）：

1. Yu L, Liu MM, Guan MQ, Wang R, Yang XR, Zhang XM, Wei JJ, Wu SF, Gu H, Fu Q, Guo JH,Li YL. Peripheral CD4+ T cell phenotype and brain microglial activation associated with cognitive heterogeneity in aged rats [J]. Immun Ageing. 2024 Nov 14;21(1):81.

2. Guan MQ, Yu L, Gu H, Fu Q, Liu MM, Li K, Yang XR, Framroze B, Guo JH, Wei JJ,Li YL. Protein hydrolysate from Atlantic salmon (Salmo salar) improves aging-associated neuroinflammation and cognitive decline in rats by reshaping the gut microbiota and Th17/Treg balance [J]. Int J Biol Macromol. 2025 Feb 19;306(Pt 1):141270.

3.Li Y, Ning L, Yin Y, Wang R, Zhang Z, Hao L, Wang B, Zhao X, Yang X, Yin L, Wu S, Guo D, Zhang C. Age-related shifts in gut microbiota contribute to cognitive decline in aged rats. Aging (Albany NY). 2020 May 1;12(9):7801-7817.

4.Li Y, Wang R, Li Q, Wang YJ, Guo J. Gut Microbiota and Alzheimer's Disease: Pathophysiology and Therapeutic Perspectives. J Alzheimers Dis. 2021;83(3):963-976.

5.Li YL, Chang XR, Ma JT, Zhao X, Yin LT, Yan LJ, Guo JH, Zhang C, Yang XR. Activation of peripheral group III metabotropic glutamate receptors suppressed formalin-induced nociception. Clin Exp Pharmacol Physiol. 2022 Feb;49(2):319-326.

6.李艷麗,楊小榮,張策,郭軍紅.抗生素對(duì)大鼠腸道菌群和認(rèn)知行為的影響[J].安徽醫(yī)科大學(xué)學(xué)報(bào),2022,57(09):1447-1452.

7.Hao L, Mi J, Song L, Guo Y,Li Y, Yin Y, Zhang C. SLC40A1 Mediates Ferroptosis and Cognitive Dysfunction in Type 1 Diabetes. Neuroscience. 2021 May 21;463:216-226.

8.Huang S, Wang J, Fan DY, Luo T,Li Y, Tu YF, Shen YY, Zeng GH, Chen DW, Wang YR, Chen LY, Wang YJ, Guo J. The association of serum uric acid with cognitive impairment and ATN biomarkers. Front Aging Neurosci. 2022 Jul 18;14:943380.